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Increasing / Optimizing the Antidepressant Dose

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If the patient is not yet responding, and if the maximum is not yet reached, consider increasing / optimizing the dosage, up to the recommended maximum dosage. 


Do not increase/maximize the antidepressant dose if:
  • There are significant side effects or drug allergies
  • Significant risk of drug interactions


Note: Lower doses or less frequent dosage increase may be better for anxious or medically compromised patients.


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