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Follow-up: Managing Antidepressants Side Effects
Click the algorithm buttons for more info.
Scale for assessing side effects
like nausea & diarrhea
Suggest general measures to manage minor illness, in more severe or prolong cases switching to another antidepressant might be necessary.
like agitation, insomnia and headaches
Wait...often gets better with time.
Try giving in the morning. In severe / more prolonged symptoms, use less activating antidepressant.
If very agitated or tremor present consider reducing or stopping the medication.
(Mostly in ages <25)
Please refer to
Assessing suicide risk
Sexual side effects
(Reduced libido, anorgasmia, delayed ejaculation, reduced erection quality)
Reducing the dose of antidepressant.
Try a different antidepressant from the table like bupropion, mirtazapine or vortioxetine.
Might consider Sildenafil, Tadalafil if not medically contraindicated.
Consider adding Wellbutrin for reduced libido providing no seizure risk.
Activation of mania / hypomania
Stop the antidepressant.
Assess for safety
Consult Psychiatry or refer the patient to Psychiatry emergency services (PES)
Mental Health Algorithms
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